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KMID : 0364820190550010046
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Korean Journal of Microbiology
2019 Volume.55 No. 1 p.46 ~ p.51
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Antimicrobial activity of fraction mixture of ethanol extracts from Eucalyptus globulus, Yucca recurvifolia, and Melaleuca alternifolia against several human skin microbes
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Lee Da-Sol
Hong In-Kee
Song Hong-Gyu
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Abstract
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This study was carried out to evaluate antimicrobial effects ofa mixture of resin fractionated ethanol extract of Eucalyptusglobulus, Yucca recurvifolia, and tea tree (Melaleuca alternifolia). The plant fraction mixture showed low minimum inhibitoryconcentration (0.24~3.32 mg/ml) against several bacteria andyeast that usually used as the target skin microbes in a cosmeticindustry, and it was more effective than antibiotics, triclosanand ampicillin. In a time-kill assay the plant fraction mixturereduced more than 92% of microbial populations during 4 h,and significantly increased leakage of nucleotides from allmicroorganisms tested. Antimicrobial effect of the plant fractionmixture was not affected by divalent cation (Mg2+and Ca2+). These results suggest that the fraction mixture of ethanol extractsof E. globulus, Y. recurvifolia, and M. alternifolia may be utilizedas an efficient preservative in cosmetics to prevent contaminationby human skin microbes.
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KEYWORD
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Eucalyptus, Yucca, antimicrobial activity, human skin microbes, tea tree
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